M Crul Selected Research

Fatigue

11/2005

Phase I and pharmacological study of the farnesyltransferase inhibitor tipifarnib (Zarnestra, R115777) in combination with gemcitabine and cisplatin in patients with advanced solid tumours.

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M Crul Research Topics

Disease

6	Neoplasms (Cancer) 09/2017 - 03/2001
1	Lymphoma (Lymphomas) 10/2018
1	Febrile Neutropenia 11/2005
1	Fatigue 11/2005
1	Neutropenia 11/2005
1	Thrombocytopenia (Thrombopenia) 11/2005
1	Neoplasm Metastasis (Metastasis) 03/2004
1	Carcinoma (Carcinomatosis) 06/2002
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 06/2002

Drug/Important Bio-Agent (IBA)

3	tipifarnib (R115777)IBA 11/2005 - 01/2002
2	Cisplatin (Platino)FDA LinkGeneric 11/2005 - 12/2002
2	Antineoplastic Agents (Antineoplastics)IBA 01/2002 - 03/2001
1	Drug CombinationsIBA 10/2018
1	Folic Acid AntagonistsIBA 09/2017
1	Methotrexate (Mexate)FDA LinkGeneric 09/2017
1	Pharmaceutical PreparationsIBA 09/2017
1	Gemcitabine FDA Link 11/2005
1	ElectrolytesIBA 11/2005
1	N- (1- (2,2- dimethyl- 1,3- dioxol- 4- yl)- 2- ((4,4- (trifluoromethoxyphenoxy)phenyl)sulfonyl)ethyl)- N- hydroxyformamideIBA 03/2004
1	Matrix Metalloproteinases (MMPs)IBA 03/2004
1	DNA (Deoxyribonucleic Acid)IBA 12/2002
1	Proteins (Proteins, Gene)FDA Link 06/2002
1	Tumor Biomarkers (Tumor Markers)IBA 06/2002
1	Carcinoembryonic AntigenIBA 06/2002
1	PlatinumIBA 06/2002
1	TransferasesIBA 06/2002
1	Codon (Codons)IBA 06/2002
1	TabletsIBA 01/2002
1	Capsules (Microcapsules)IBA 01/2002

Therapy/Procedure

1	Drug Therapy (Chemotherapy) 10/2018
1	Therapeutics 10/2018
1	Oral Administration 06/2002